Clinical Trials Directory

Trials / Completed

CompletedNCT01233115

LOC387715/HTRA1 and the Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal Vasculopathy

LOC387715/HTRA1 Variants and the Response to Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal Vasculopathy

Status
Completed
Phase
Study type
Observational
Enrollment
70 (actual)
Sponsor
Kyungpook National University Hospital · Academic / Other
Sex
All
Age
60 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This study is to investigate whether there is an association of the LOC387715/HTRA1 variants with response to treatment with combined photodynamic therapy and intravitreal bevacizumab for patients with polypoidal choroidal vasculopathy.

Detailed description

This is a retrospective cohort study comprised of 70 eyes being treated for polypoidal choroidal vasculopathy with combined photodynamic therapy and intravitreal bevacizumab injections. Patients were genotyped for the LOC387715 (rs10490924) and the HTRA1 gene polymorphism (rs11200638).

Conditions

Timeline

Start date
2010-10-01
Primary completion
2011-08-01
Completion
2011-08-01
First posted
2010-11-03
Last updated
2011-08-30

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT01233115. Inclusion in this directory is not an endorsement.

LOC387715/HTRA1 and the Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal Vasculopathy (NCT01233115) · Clinical Trials Directory