Clinical Trials Directory

Trials / Terminated

TerminatedNCT01230931

Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel)

Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
26 (actual)
Sponsor
The University of Texas Health Science Center, Houston · Academic / Other
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine whether surgical hemostats can minimize blood loss, need for allogeneic blood transfusions and their associated risks, and costs in patients with certain acetabular fractures requiring operative fixation via a non-extensile Kocher-Langenbeck surgical approach. Since surgical hemostats and other topical agents like platelet gel products have also been linked with improved wound healing, incidence of wound dehiscence and/or infections will also be examined. The investigators primary hypothesis is the topical hemostat will result in lower blood losses intraoperatively and fewer units of perioperative blood product transfused.

Conditions

Interventions

TypeNameDescription
DEVICEVitagelVitagel (by Stryker) is a topical surgical hemostat spray that results in coagulation. The components are as follows: autogenous blood is drawn and centrifuged to produce a sample of platelets and growth factors; this is combined with a bovine thrombin and collagen solution. When the two are applied together, it produces the hemostatic effect.
PROCEDUREStandard of careStandard of care for hemostasis in acetabular surgery includes electrocautery/ligation of bleeding vessels, fracture reduction and stabilization, cell-saver, lap packing.

Timeline

Start date
2010-10-01
Primary completion
2012-04-01
Completion
2012-04-01
First posted
2010-10-29
Last updated
2018-12-11
Results posted
2018-11-15

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT01230931. Inclusion in this directory is not an endorsement.