NCT01228123

Clinical Trial Comparing Continuous Versus Intermittent Hemodialysis in ICU Patients

Prospective Randomised Clinical Trial of the Effect of Continuous Versus Intermittent Renal Replacement Therapy on the Mortality and Outcome of Acute Renal Failure in ICU Patients

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 252 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The mortality of acute renal failure (ARF) remains to be high (around 60-70%) despite manifold improvements in ICU care. At present, it is not clear if the method chosen for renal replacement therapy, i.e. intermittent haemodialysis (IHD) or continuous haemofiltration (CVVH), might impact on the outcome of these patients. For this purpose, a prospective randomised clinical study of the effect of continuous versus intermittent renal replacement therapy on the mortality and outcome of acute renal failure will be performed.

Detailed description

please see above

Conditions

• Acute Renal Failure

Interventions

Type	Name	Description
OTHER	RRT for acute kidney failure using the CVVH method	patients randomized to receive CVVH
OTHER	RRT for acute kidney failure using the IHD (intermittent HD)	patients randomized to receive IHD

Timeline

• Start date: 2002-01-01
• Primary completion: 2007-10-01
• Completion: 2008-01-01
• First posted: 2010-10-26
• Last updated: 2011-05-25

Locations

1 site across 1 country: Germany