NCT01223729

Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 67 (planned)
• Sponsor: University of Catania · Academic / Other
• Sex: All
• Age: 34 Years – 67 Years
• Healthy volunteers: —

Summary

Minimal hepatic encephalopathy represents a common complication present in well-compensated cirrhotic patients that impairs patients daily functioning and health-related quality of life. Acetyl-L-carnitine has been shown to be useful in improving blood ammonia and cognitive functions in cirrhotic patients with minimal hepatic encephalopathy. This study evaluated the effects of acetyl-L-carnitine treatment on health related quality of life and on depression in patients with minimal hepatic encephalopathy.

Conditions

• Minimal Hepatic Encephalopathy

Interventions

Type	Name	Description
DRUG	Acetyl-L-Carnitine	2 g acetyl-L carnitine twice a day
OTHER	placebo	placebo twice per day

Timeline

• Start date: 2002-04-01
• Completion: 2005-11-01
• First posted: 2010-10-19
• Last updated: 2010-10-19

Locations

1 site across 1 country: Italy