NCT01219465

Umbilical Cord Mesenchymal Stem Cells Infusion for Initial Type 1 Diabetes Mellitus

Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cells Infusion for Initial Type 1 Diabetes

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Qingdao University · Academic / Other
• Sex: All
• Age: 3 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether umbilical cord Mesenchymal Stem Cells of treatment for initial type 1 diabetes is safe and effective.

Detailed description

Type 1 diabetes mellitus (T1DM)is characterized by the autoimmune destruction of the pancreatic β cells.Patients require multiple daily insulin injections throughout their lives as well as close monitoring of their diet and blood sugar levels to prevent complications. The investigators hope umbilical cord Mesenchymal Stem Cells could not only address the need for β-cell replacement but also control of the autoimmune response to β cells.

Conditions

• Diabetes Mellitus
• Diabetes Mellitus, Type 1
• Mesenchymal Stem Cells
• Umbilical Cord

Interventions

Type	Name	Description
BIOLOGICAL	umbilical cord mesenchymal stem cells	Transfusion of the umbilical cord mesenchymal stem cells (2 x 107 cells) intravenously.

Timeline

• Start date: 2010-09-01
• Primary completion: 2012-09-01
• Completion: 2012-12-01
• First posted: 2010-10-13
• Last updated: 2010-10-13

Locations

1 site across 1 country: China