Trials / Completed
CompletedNCT01218347
Influence of Organic Anion Transporting Polypeptide1B1(OATP1B1) Genotype on Rosuvastatin PK, PD and Lipid Profiles
Influence of OATP1B1 Genotype on the Pharmacokinetics,Lipid Lowering Effect, and Lipid Profiles After Rosuvastatin Administration
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 34 (estimated)
- Sponsor
- Seoul National University Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This study aimed to explore the influence of organic anion transporting polypeptide1B1 (OATP1B1) genotype on pharmacokinetics, lipid lowering effect and lipid profiles after rosuvastatin administration.
Detailed description
Open, one arm, single sequence study for healthy volunteers are investigated. Thirty four subjects may be enrolled. Rosuvastatin are administered once a day for 21 days. Before and after rosuvastatin administration, PK, PD and lipid profiles are investigated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Rosuvastatin | 20 mg once daily for 21 days |
Timeline
- Start date
- 2010-10-01
- Primary completion
- 2010-12-01
- Completion
- 2010-12-01
- First posted
- 2010-10-11
- Last updated
- 2011-01-06
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01218347. Inclusion in this directory is not an endorsement.