NCT01216410

Prevention of Intraoperative Nausea and Vomiting During Cesarean Section

The Effect of Adding Metoclopramide and Ondansetron to a Prophylactic Phenylephrine Infusion for the Management of Nausea and Vomiting Associated With Spinal Anesthesia for Cesarean Section

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 306 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.

Conditions

• Cesarean Delivery

Interventions

Type	Name	Description
DRUG	Metoclopramide	Prophylactic Metoclopramide 10 mg given before spinal together with prophylactic phenylephrine infusion
DRUG	Phenylephrine infusion	Prophylactic phenylephrine infusion after spinal and placebo antiemetics
DRUG	Combination Group	Metoclopramide and ondansetron prophylaxis with phenylephrine infusion

Timeline

• Start date: 2008-12-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2010-10-07
• Last updated: 2014-08-06
• Results posted: 2013-03-25

Locations

1 site across 1 country: United States