Clinical Trials Directory

Trials / Completed

CompletedNCT01215747

Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis

International Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Efficacy and Safety of KIACTA in Preventing Renal Function Decline in Patients With AA Amyloidosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
261 (actual)
Sponsor
C.T. Development America, Inc. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to assess the efficacy and safety of treatment with Kiacta in adult patients with AA Amyloidosis.

Conditions

Interventions

TypeNameDescription
DRUGKIACTA (eprodisate disodium)Orally 1 to 3 capsules (Kiacta 400 mg) twice daily and adjusted as per the Creatine Clearance (CrCl) level increases or decreases.
DRUGPlaceboOrally 1 to 3 capsules (placebo) twice daily and adjusted as per the Creatine Clearance (CrCl) level increases or decreases:

Timeline

Start date
2010-11-01
Primary completion
2016-01-01
Completion
2016-03-01
First posted
2010-10-06
Last updated
2016-03-10

Locations

46 sites across 23 countries: United States, Belgium, Egypt, Estonia, Finland, France, Georgia, Germany, India, Israel, Italy, Latvia, Lithuania, Netherlands, Peru, Poland, Russia, Spain, Sweden, Tunisia, Turkey (Türkiye), Ukraine, United Kingdom

Source: ClinicalTrials.gov record NCT01215747. Inclusion in this directory is not an endorsement.