NCT01215370

Pea Protein and Postprandial Response (PEA)

Effect of Arginine-rich Dietary Protein on Postprandial Metabolism, Inflammation and Endothelial Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Wageningen University · Academic / Other
• Sex: Male
• Age: 45 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The main objective is to investigate the postprandial effect of arginine-rich protein (i.e. pea-protein) on metabolic control, inflammation and endothelial function after a high-fat meal in subjects with characteristics of the metabolic syndrome.

Detailed description

Arginine is potential interesting considering the metabolic syndrome. Studies so far indicated both long-term effects, as well as acute - postprandial - actions; especially when metabolism is already challenged, e.g. in diabetic patients or after a high-fat meal. If arginine-rich proteins are equally effective is not known. Therefore we are interested in the effect of (arginine rich) protein on postprandial (dys)metabolism, inflammation and endothelial function, within 6 hours after a meal.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
OTHER	High-fat shake with Pea protein	Shake containing 95 gram of fat, additive 30 gram pea protein
OTHER	High-fat shake with Pea protein hydrolysate	Shake containing 95 gram of fat, additive 30 gram gluten protein hydrolysate
OTHER	High-fat shake - Control	Shake containing 95 gram of fat, no protein additive
OTHER	High-fat shake with Gluten protein	Shake containing 95 gram of fat, additive 30 gram gluten protein.
OTHER	High-fat shake with Gluten protein hydrolysate	Shake containing 95 gram of fat, additive 30 gram gluten gluten hydrolysate

Timeline

• Start date: 2010-09-01
• Primary completion: 2011-01-01
• Completion: 2011-01-01
• First posted: 2010-10-06
• Last updated: 2011-09-07

Locations

1 site across 1 country: Netherlands