NCT01214070

Functional Vision in TBI

Functional Vision Consequences of Rehabilitation for TBI Vision Loss

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 110 (estimated)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 20 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to test functional vision outcome measures that reflect the loss in everyday life tasks that require vision and that are sensitive to changes after a course of vision rehabilitation in Veterans/participants with TBI.

Detailed description

Traumatic brain injury (TBI) can cause vision loss because of diffuse or focal neuronal injury. Vision can be compromised because of local injury to one or both optic nerves, diffuse brain injury, and/or limitation in eye movements because of dysfunction of cranial nerves. These typical injuries may compromise any of the neural pathways that subserve afferent or efferent visual function. Self-reports of vision loss include diplopia, visual field loss, light sensitivity, reading problems and contrast sensitivity (color and luminance) loss. This project will pursue the following aims: 1) Identify the relationship between functional vision loss in everyday vision tasks (reading, visual search, way finding) and the characteristics of potential visual impairment (visual acuity, contrast sensitivity, visual fields, stereoacuity, eye movement disorders) associated with TBI; and 2) Determine the ability of the vision rehabilitation interventions (both monotherapy and combination therapy) to improve functional vision outcome measures that reflect everyday visual tasks. The vision rehabilitation interventions incorporated into this study will be Vision Restoration Therapy, NVT Eye Scanning Therapy, and standard Eccentric Viewing Training. These therapies are rehabilitative interventions prescribed for Veterans in Polytrauma Rehabilitation Centers, Blind Rehabilitation Centers, and advocated for VA Medical Center TBI clinics.

Conditions

• Brain Injuries
• Visually Impaired Persons

Interventions

Type	Name	Description
OTHER	Vision Restoration Therapy	Therapy that enhances the neuronal plasticity of the visual system
BEHAVIORAL	NVT Eye Scanning Therapy	Therapy that trains eye and head scanning into the blind hemianoptic visual field
BEHAVIORAL	Eccentric Viewing Training	Therapy that trains the person to compensate for visual field loss by learning to move the visual field loss to the position that is least likely to impact the current visual task
BEHAVIORAL	Sham	Therapy that encourages subjects to do daily visual tasks at home while having no training or intended intervention benefit

Timeline

• Start date: 2012-06-01
• Primary completion: 2013-11-21
• Completion: 2013-11-21
• First posted: 2010-10-04
• Last updated: 2017-06-16

Locations

1 site across 1 country: United States