NCT01212965

Selenium in the Treatment of Complicated Lymphatic Malformations

Pilot Clinical Trial to Estimate the Safety and Efficacy of Selenium in the Treatment of Complicated Lymphatic Malformations in Adolescents and Young Adults

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Medical College of Wisconsin · Academic / Other
• Sex: All
• Age: 14 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The investigators propose a pilot trial to obtain preliminary information regarding the safety and response rate of patients with symptomatic lymphatic malformations treated with oral Selenium. Information obtained in this pilot trial will be used to plan future phase 2 clinical trials. Hypotheses: * Selenium will be safe and efficacious in the treatment of adolescents and young adults with symptomatic lymphatic malformations * Disease response will correlate with serum levels of selenium and blood levels of antioxidants essential to selenium metabolism.

Conditions

• Lymphatic Malformations

Interventions

Type	Name	Description
DRUG	Selenium	400 μg once a day for 6 months by mouth

Timeline

• Start date: 2010-09-01
• Primary completion: 2011-09-01
• Completion: 2012-11-01
• First posted: 2010-10-01
• Last updated: 2013-04-23

Locations

1 site across 1 country: United States