Clinical Trials Directory

Trials / Completed

CompletedNCT01212523

Effects of Propofol and Isoflurane on Pulmonary Vascular Resistance

Randomised Cross-over Pilot Study to Determine the Effects of Isoflurane and Propofol on Pulmonary Vascular Resistance in Children With Pulmonary Hypertension.

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
10 (actual)
Sponsor
University Hospitals Bristol and Weston NHS Foundation Trust · Academic / Other
Sex
All
Age
3 Months – 16 Years
Healthy volunteers
Not accepted

Summary

The investigators hypothesize that there is no difference between the effects of isoflurane and propofol anaesthesia on pulmonary vascular resistance (PVR).

Conditions

Interventions

TypeNameDescription
DRUGpropofol and isofluraneboth drugs administered at age-related dose and titrated to effect. maximum dose of propofol 15 mg/kg/hr, maximum dose of isoflurane 1.5 MAC

Timeline

Start date
2009-11-01
Primary completion
2011-12-01
Completion
2011-12-01
First posted
2010-09-30
Last updated
2011-12-15

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT01212523. Inclusion in this directory is not an endorsement.