NCT01211366

Use of Cell Salvage Post-operatively in Infants to Decrease Use of Allogeneic Blood Product Transfusions

Post-operative Infusion of Intra-operative Cell Salvage Reduces Allogeneic Blood Product Transfusions and Volume Resuscitation in Pediatric Cardiac Surgery and Improves Clinical Outcomes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 106 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators. This will reduce the need for allogeneic blood products as well as crystalloid and colloid infusions and thus decrease the length of ventilation and intensive care duration for these infants.

Conditions

• Transfusion

Interventions

Type	Name	Description
OTHER	Cell Saver RBCs	Use of cell saver RBCs to decrease the infusion of allogeneic PRBCs, crystalloid, and colloid in post-operative infants following CPB as needed for hemodynamic instability
OTHER	Conventional volume infusion	Infusion of allogeneic PRBCs, crystalloid, and colloid as needed for hemodynamic instability

Timeline

• Start date: 2010-10-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2010-09-29
• Last updated: 2012-02-13

Locations

1 site across 1 country: United States