NCT01211106

Integrated vs Sequential Treatment for PTSD and Addiction

Integrated vs Sequential Treatment for PTSD and Addiction Among OEF/OIF Veterans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 183 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The investigators are examining different treatment strategies of helping patients with PTSD and addiction.

Detailed description

The investigators hypothesize that Veterans in the integrated conditions will show greater reductions in substance abuse and PTSD symptom severity at the end of treatment and at 6 and 9 month follow-ups. The investigators further hypothesize that offering Veterans Prolonged Exposure (PE) at the onset of treatment in the integrated condition will leader to greater retention and satisfaction than in the sequential treatment design.

Conditions

• PTSD
• Substance Addiction

Interventions

Type	Name	Description
BEHAVIORAL	Prolonged Exposure	Although almost every form of psychotherapy has been advocated for PTSD, all evidence-based psychotherapies for PTSD are CBT programs that include variants of exposure therapy (Prolonged Exposure), cognitive therapy (CT), stress inoculation training (SIT), eye movement desensitization and reprocessing (EMDR), or combinations of these procedures. Exposure therapy involves helping PTSD sufferers to gradually confront distressing trauma-related memories and reminders to facilitate successful emotional processing of the trauma memory and reduction of associated distress. Most exposure therapy programs include both imaginable confrontation with the traumatic memories and in vivo exposure to trauma reminders.
BEHAVIORAL	Motivational Enhancement Therapy	Motivational Interviewing (MI) is defined as a client-centered, directive method for enhancing intrinsic motivation to change by exploring and resolving ambivalence. MI is characterized by its spirit, which is defined as collaboration with the client, evocation of the client's own perceptions, goals, and values, and respect for the client's autonomy.

Timeline

• Start date: 2011-02-01
• Primary completion: 2016-03-01
• Completion: 2016-07-01
• First posted: 2010-09-29
• Last updated: 2017-03-09
• Results posted: 2017-03-09

Locations

2 sites across 1 country: United States