Trials / Completed
CompletedNCT01210404
Drug Interaction Study Of Filibuvir With Methadone Among Subjects On Chronic Methadone Maintenance
Open Label Single Sequence Study To Estimate The Effect Of Filibuvir (PF-00868554) On S-And R-Methadone In Subjects Receiving Chronic Methadone Treatment And To Evaluate The Pharmacokinetics Of Filibuvir
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Pfizer · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
Filibuvir, a CYP3A4 inhibitor is being developed for the treatment of chronic Hepatitis C infection. Given the likelihood of co administration of filibuvir and methadone, this study will evaluate the effect of filibuvir on the pharmacokinetics of R/S Methadone.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | filibuvir | Filibuvir, 600mg bid administered along with methadone on days 2-11 |
Timeline
- Start date
- 2011-02-01
- Primary completion
- 2011-05-01
- Completion
- 2011-06-01
- First posted
- 2010-09-28
- Last updated
- 2011-06-07
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01210404. Inclusion in this directory is not an endorsement.