NCT01204554

Microcirculation in Perforator Flaps. Enhancing Tissue Survival

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.

Detailed description

Perforator flaps are increasingly used in reconstructive surgery both as pedicled and free flaps, mostly because of reduced donor site morbidity and superior aesthetic result. However, the there is still much to learn about the hemodynamic changes within these flaps.The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.

Conditions

• Reconstructive Surgery
• Microcirculation

Interventions

Type	Name	Description
DRUG	Indocyanine green (ICG)	a water-soluble dye that binds to plasma proteins and remains in the intravascular space after intravenous injection.ICG has a normal plasma half life of 3-4 min. Dosage planned is 0 .5 mg/kg dose of ICG resolved in 5 % dextrose 2 mg /ml.

Timeline

• Start date: 2008-09-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2010-09-17
• Last updated: 2010-09-17

Locations

1 site across 1 country: Norway