Clinical Trials Directory

Trials / Completed

CompletedNCT01204151

Teaching Math Skills to Individuals With Fragile X Syndrome

Evaluating a Brief Intensive Intervention for Individuals With Fragile X Syndrome

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Stanford University · Academic / Other
Sex
All
Age
10 Years – 23 Years
Healthy volunteers
Not accepted

Summary

Children with FXS are predisposed to manifesting a particular profile of intellectual strengths and weaknesses, including specific deficits in math, visual-spatial skills, executive functioning, and social skills. Until now, intensive behavioral interventions have not been targeted to syndrome-specific weaknesses. In the present study we will develop and evaluate behavioral strategies to aid skill acquisition in children with FXS.

Detailed description

There are no experimental data of skill acquisition using matching-to-sample techniques (or any other specific cognitive intervention) conducted with individuals with FXS. Further, no studies have been conducted to examine the possible underlying or mediating brain processes involved during matching-to-sample skill acquisition in children with FXS or any other neurodevelopmental disorder. Previous pilot data have indicated that the computerized match-to-sample procedure, even when conducted in time-limited sessions, may significantly help individuals with FXS learn new skills. We plan to utilize brain imaging methodology to compare functional connectivity networks for those who pass and those who fail the equivalence test. 30 subjects with FXS and 30 control subjects with idiopathic developmental disability will be enrolled in the study. All subjects will be enrolled at Stanford.

Conditions

Interventions

TypeNameDescription
BEHAVIORALdiscrete-trial training

Timeline

Start date
2008-09-01
Primary completion
2013-07-01
Completion
2013-07-01
First posted
2010-09-17
Last updated
2019-05-09

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01204151. Inclusion in this directory is not an endorsement.