NCT01198574

Sub-clinical Inflammation and Iron Supplementation

The Role of Sub-clinical Inflammation on the Iron Status of Myanmar Anaemic Adolescent Schoolgirls During Iron and Vitamin A Supplementation

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 402 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: Female
• Age: 12 Years – 19 Years
• Healthy volunteers: Accepted

Summary

Anemia and vitamin A deficiency (VAD) are major nutritional problems in the world and also in Myanmar. Both nutrient deficiencies result from interaction of several causal factors, and a better understanding of the etiology to interpret the prevalence and to formulate appropriate measures to reduce these deficiencies is necessary. There is a growing concern on the role of sub-clinical inflammation on the nutritional status indicators during the nutritional status assessment. However, there is lack of information on the role of inflammation on the iron supplementation. The adolescent period is a window of opportunity to improve the preconceptional iron status of the girls and recently gained much attention. The purpose of the study is to understand the role of inflammation on iron and vitamin A status during iron and vitamin A supplementation. The findings will show the extent to which iron supplementation has been hampered by inflammation and to formulate the necessary measures to overcome the interference.

Conditions

• Anemia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Iron group	Ferrous fumarate, 60 mg, weekly dose
DIETARY_SUPPLEMENT	Vitamin A group	Retinol, weekly dose, 15,000 IU
DIETARY_SUPPLEMENT	Iron and vitamin A group	Ferrous fumarate, Retinol combination group, weekly dose
DIETARY_SUPPLEMENT	Placebo group	folic acid only as placebo group

Timeline

• Start date: 2010-07-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2010-09-10
• Last updated: 2012-05-22
• Results posted: 2012-05-16

Locations

1 site across 1 country: Burma