NCT01197781

Evaluation of the Drug-drug Interaction Between FosD and Verapamil When Taken Together in Healthy Volunteers

An Open-label, Single-Centre Study to Assess the Pharmacokinetics of R406 in Healthy Volunteers When Fostamatinib Disodium 150 mg is Administered Alone and in Combination With Verapamil

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: AstraZeneca · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This Study evaluates the possible drug interaction between FosD and verapamil when taken together.

Detailed description

An Open-label, Single-Centre Study to Assess the Pharmacokinetics of R406 in Healthy Volunteers when Fostamatinib Disodium 150 mg is Administered Alone and in Combination with Verapamil.

Conditions

• Drug Drug Interactions
• Healthy Volunteers

Interventions

Type	Name	Description
DRUG	FOSTAMATIN	Oral tablets - single dose
DRUG	Verapamil	Oral tablets - administered 3 times daily over 4 days

Timeline

• Start date: 2010-09-01
• Primary completion: 2010-10-01
• Completion: 2010-10-01
• First posted: 2010-09-09
• Last updated: 2010-11-23

Locations

1 site across 1 country: United States