NCT01196572

Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures

Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Sheba Medical Center · Other Government
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether laser internal urethrotomy (IU) is as efficient as cold knife internal urethrotomy for treatment of anterior urethral strictures regarding post operative urination outflow, stricture recurrence rate and possible post- operative complications

Detailed description

The current surgical treatment for anterior urethral stricture includes internal urethrotomy (IU) by cold knife. Recurrence rate after such procedure is quoted as 35-70% in 2 to 5 years follow-up. Possible surgical alternative procedures include: open surgical urethral re-construction, urethral stents usage \& laser IU. According to existing data (Nd-YAG laser- retrospective) the recurrence rate after laser IU is far better comparing to cold knife urethrotomy. The current research intends to address this question using prospective randomized methods.

Conditions

• Urethral Strictures

Interventions

Type	Name	Description
PROCEDURE	Internal Urethrotomy	surgical incision of urethral stricture using endoscopic cold knife vs. endoscopic laser

Timeline

• Start date: 2010-09-01
• Primary completion: 2012-09-01
• Completion: 2013-09-01
• First posted: 2010-09-08
• Last updated: 2011-08-09

Locations

1 site across 1 country: Israel