Clinical Trials Directory

Trials / Completed

CompletedNCT01193257

Study Comparing Orteronel Plus Prednisone in Participants With Metastatic Castration-Resistant Prostate Cancer.

A Phase 3, Randomized, Double-Blind, Multicenter Trial Comparing Orteronel (TAK-700) Plus Prednisone With Placebo Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer That Has Progressed During or Following Docetaxel-based Therapy.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,099 (actual)
Sponsor
Millennium Pharmaceuticals, Inc. · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a randomized, double-blind, multicenter, phase 3 study evaluating orteronel plus prednisone compared with placebo plus prednisone in men with metastatic, castration-resistant prostate cancer (mCRPC) that has progressed following Docetaxel-based therapy

Conditions

Interventions

TypeNameDescription
DRUGOrteronelOrteronel tablets
DRUGPrednisonePrednisone tablets
DRUGOrteronel PlaceboOrteronel placebo-matching tablets

Timeline

Start date
2010-11-15
Primary completion
2013-05-16
Completion
2016-02-29
First posted
2010-09-01
Last updated
2018-12-19
Results posted
2018-12-19

Locations

78 sites across 14 countries: United States, Australia, Belgium, Canada, Czechia, Estonia, Finland, France, Greece, Hungary, Italy, Netherlands, Poland, Spain

Source: ClinicalTrials.gov record NCT01193257. Inclusion in this directory is not an endorsement.