Trials / Completed
CompletedNCT01191827
fMRI Cholinergic Mechanisms in Schizophrenia
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (actual)
- Sponsor
- US Department of Veterans Affairs · Federal
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to determine how clozapine treatment improves neuronal measures of sensory gating in subjects with schizophrenia.
Detailed description
This study will use functional magnetic resonance imaging (fMRI) to study patients treated with risperidone, a commonly used neuroleptic that does not improves sensory gating, to those treated with clozapine to determine which brain areas are involved in clozapine's normalization of sensory gating in schizophrenia.
Conditions
Timeline
- Start date
- 2008-10-01
- Primary completion
- 2011-12-01
- Completion
- 2011-12-01
- First posted
- 2010-08-31
- Last updated
- 2015-05-15
- Results posted
- 2015-05-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01191827. Inclusion in this directory is not an endorsement.