NCT01189682

Impact of Tegaderm HP and CHG in Major Catheter Related Infections and Dressing Detachment

Impact of Tegaderm HP and Tegaderm CHG in Major Catheter Related Infections and Dressing Detachment in ICU Patients a Prospective Randomized Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,960 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Catheter related infection is a frequent and life threatening event in ICU. A chlorhexidine impregnated sponge has been proven to reduce the rate of major catheter related infections in ICU patients (HR=0.39, p=0.03) (Timsit Jama 2009). However, dressings are detached in 40% of cases before planned changes and the rate of unplanned dressing is significantly associated with the major catheter related infections. Primary objective: To demonstrate that Tegaderm CHG, a new CHG impregnated dressing decrease the rate of major catheter related infection as compared to non impregnated dressings and to demonstrate that highly adhesive dressing decrease the rate of detached dressings. Secondary objectives: * To demonstrate that the use of high performance dressing decrease the rate of unstuck dressing and the rate of catheter infections. * To evaluate the tolerance of CHG impregnated gel dressings (Tegaderm CHG). * To calculate the cost saving of each dressings

Detailed description

Inclusion criteria: Patients older than 18 years old with central venous who need a central vein and/or an arterial catheter for an expected duration of more than 48 hours.

Conditions

• Catheter-Related Infections

Interventions

Type	Name	Description
PROCEDURE	Tegaderm, Tegaderm HP, Tegaderm CHG	dressings on catheters

Timeline

• Start date: 2010-04-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2010-08-27
• Last updated: 2013-10-21

Locations

1 site across 1 country: France