NCT01187823

The Effect of Adaptive Servo Ventilation and Oxygen Therapy in Central Sleep Apnea Patients

Comparison of Adaptive Servo Ventilation(Bipap® Auto SV Advanced) and Oxgen Therapy in Chronic Heart Failure Patients Complicated With Central Sleep Apnea

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Kyoto University, Graduate School of Medicine · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the effects of Adaptive Servo Ventilation (Bipap® auto SV Advanced) and oxygen therapy in chronic heart failure patients complicated with central sleep apnea.

Detailed description

Central sleep apnea(CSA) is associated with chronic heart failure(CHF). At present, both of nocturnal oxygen therapy and adaptive servo ventilation(ASV) are recognized as effective modalities. However,in fact, majority of CHF patients are complicated not only with CSA but with obstructive sleep apnea(OSA). Recently, Philips developed Bipap® auto SV Advanced for such patients. It has auto-CPAP function as the modality of OSAS, in addition to ASV function. The present study is prospective randomised study to compare the effects of nocturnal oxygen therapy and Bipap® auto SV Advanced.

Conditions

• Chronic Heart Failure
• Sleep Apnea

Interventions

Type	Name	Description
DEVICE	Adaptive servo ventilation	Nocturnal use of Adaptive servo ventilation
DEVICE	Nocturnal oxygen	Nocturnal use of oxygen

Timeline

• Start date: 2010-12-01
• Primary completion: 2013-12-01
• Completion: 2014-03-01
• First posted: 2010-08-24
• Last updated: 2015-04-14

Locations

1 site across 1 country: Japan