Clinical Trials Directory

Trials / Completed

CompletedNCT01187212

Sorafenib Trial in Advanced and/or Recurrent Gastric Adenocarcinoma: Treatment Evaluation: STARGATE

A Randomized Phase II Study of Capecitabine and Cisplatin (XP) +/- Sorafenib (Nexavar®) in Patients With Advanced Gastric Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
195 (actual)
Sponsor
Asan Medical Center · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study investigates the efficacy and safety profiles of sorafenib in combination of capecitabine and cisplatin, one of standard chemotherapy regimens in patients with advanced gastric cancer.

Conditions

Interventions

TypeNameDescription
DRUGCapecitabine/Cisplatin + SorafenibCapecitabine 800 mg / m² po bid (D1-14) Cisplatin 60 mg / m² IV Day 1 Sorafenib 400 mg p.o. bid continuous dosing
DRUGCapecitabine/CisplatinCapecitabine 1000 milligram (mg) / m² po bid (D1-14) Cisplatin 80 mg / m² IV Day 1

Timeline

Start date
2010-08-01
Primary completion
2013-11-01
Completion
2014-08-01
First posted
2010-08-24
Last updated
2020-01-07

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT01187212. Inclusion in this directory is not an endorsement.

Sorafenib Trial in Advanced and/or Recurrent Gastric Adenocarcinoma: Treatment Evaluation: STARGATE (NCT01187212) · Clinical Trials Directory