NCT01186276

Dietary Maneuvers to Reduce Production of Colon-Derived Uremic Solutes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will assess whether dietary fiber supplements can reduce the production of chemicals which are produced by colon bacteria and normally excreted from the body by the kidney, but build up in the body in patients on hemodialysis.

Detailed description

The study procedures will consist of: * taking a dietary supplement containing either fiber or starch (starch serves as a control for fiber) for six weeks. The fiber dose initially employed will be 30 g/day of high amylose corn and the control starch dose employed will be 30 g/day of waxy corn starch. Supplements which come in dry powder form will be mixed in liquid or food for consumption. * filling out a food record and a quality of life questionnaire * keeping a diary of any gi symptoms * collecting samples of blood, spent dialysate, urine(if the patient still makes urine) and stool.

Conditions

• Kidney Failure, Chronic

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fiber	Dietary fiber supplements to be consumed daily for 6 weeks.
DIETARY_SUPPLEMENT	Corn starch	Corn starch to be consumed daily for 6 weeks. This will serve as the control/placebo arm.

Timeline

• Start date: 2010-07-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2010-08-23
• Last updated: 2022-08-25

Locations

3 sites across 1 country: United States