Trials / Completed
CompletedNCT01183052
Mitochondrial Dysfunction and Oxidative Stress in Chronic Obstructive Pulmonary Disease (COPD) Patients
Mitochondrial Respiratory Chain and Peripheral Muscle Dysfunction in COPD Patients
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- 5 Santé · Academic / Other
- Sex
- All
- Age
- 50 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to understand the underlying mechanisms of improved exercise tolerance in COPD patients after training program.
Detailed description
Training protocol used is based on recommendations (Nici et al., 2006) and was previously used in our group (Varray et al., 1991; Vallet et al., 1997). A minimum of 20 sessions in 4-6 weeks were proposed. The exercise intensity of exercise corresponds to target heart rate at ventilatory threshold measured during incremental exercise test. Training at this intensity allowed us to individualize effort for each patient.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Training | 20 sessions of training |
Timeline
- Start date
- 2009-06-01
- Primary completion
- 2010-12-01
- Completion
- 2010-12-01
- First posted
- 2010-08-17
- Last updated
- 2012-09-05
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT01183052. Inclusion in this directory is not an endorsement.