Clinical Trials Directory

Trials / Completed

CompletedNCT01181453

Pivotal Trial of Dermagraft(R) to Treat Diabetic Foot Ulcers

A Prospective, Multicenter, Randomized, Single-Blind, Phase III, Clinical Investigation of Dermagraft(R) in Patients With Plantar Diabetic Foot Ulcers

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
314 (actual)
Sponsor
Organogenesis · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study randomly assigns patients with diabetic foot ulcers to receive standard therapy (surgical debridement, saline-moistened gauze and offloading) alone or standard therapy plus Dermagraft(R). Dermagraft is a device containing live human fibroblasts grown on an absorbable Vicryl mesh. Patients are seen weekly until they heal or the 12-week treatment period is complete.

Conditions

Interventions

TypeNameDescription
DEVICEDermagraftWeekly application of Dermagraft(R) with standard care
OTHERComparatorWeekly application of standard care

Timeline

Start date
1998-12-01
Primary completion
2000-03-01
Completion
2000-03-01
First posted
2010-08-13
Last updated
2018-05-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01181453. Inclusion in this directory is not an endorsement.