Clinical Trials Directory

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UnknownNCT01180426

Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia

The TOPAZ Study: A Long-Term Extension Study in Elderly Subjects With Relapsed/Refractory Acute Myeloid Leukemia to Allow Continued Therapy With Tosedostat

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Chroma Therapeutics · Industry
Sex
All
Age
60 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the long-term efficacy and safety profile of tosedostat in elderly patients suffering from refractory or relapsed Acute Myeloid Leukemia.

Detailed description

Extension protocol to the OPAL Study (CHR-2797-038). Study mimics normal clinical practice; few procedures and visits are therefore mandated by the protocol. Timing of bone marrow assessment is also left at the investigator's discretion.

Conditions

Interventions

TypeNameDescription
DRUGCHR-2797120mg once daily oral for 48 weeks

Timeline

Start date
2010-06-01
Primary completion
2013-06-01
Completion
2013-06-01
First posted
2010-08-12
Last updated
2012-02-15

Locations

6 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01180426. Inclusion in this directory is not an endorsement.