NCT01175655

A Study to Evaluate the Potential of Mesenchymal Stromal Cells to Treat Obliterative Bronchiolitis After Lung Transplantation

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: The Prince Charles Hospital · Other Government
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The primary aim of this study is to establish the safety of infusions of Mesenchymal Stromal Cells (MSC) from related or unrelated Human Leukocyte Antigen (HLA) identical or HLA mismatched donors in the management of bronchiolitis obliterans syndrome after lung transplantation.

Conditions

• Bronchiolitis Obliterans
• Lung Transplantation

Interventions

Type	Name	Description
OTHER	MSC	mesenchymal stromal cells (MSC), aiming for 2 x 106 /kg cells recipient body weight, aiming for a frequency of twice weekly for two weeks

Timeline

• Start date: 2010-02-01
• Primary completion: 2015-07-01
• Completion: 2016-07-01
• First posted: 2010-08-05
• Last updated: 2022-04-26

Locations

2 sites across 1 country: Australia