NCT01172782

The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Korea University Anam Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 72 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the adequate dose of intrathecal hydromorphone injection for postoperative pain relief after knee arthroscopic surgery.

Detailed description

Sixty patients who were undergoing unilateral knee arthroscopy randomly received unilateral spinal anesthesia with 0.5% hyperbaric bupivacaine 6 mg combined with normal saline 0.05 mL or hydromorphone 2.5, 5 or, 10 μg/0.05 mL. The verbal numerical rating scale (VNRS) pain scores were measured at 30 minutes and 2, 4, 6, 12 and 24 hours postoperatively, and the side effects of hydromorphone were recorded.

Conditions

• Pain Measurement
• Visual Analog Pain Scale

Interventions

Type	Name	Description
DRUG	Hydromorphone	2.5, 5, 10 ug of hydromorphone, intrathecal injection, single injection. duration of intrathecal injection are not fully studied.

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-02-01
• Completion: 2010-07-01
• First posted: 2010-07-30
• Last updated: 2011-06-27