NCT01172431

Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency

A Comparison of Indapamide SR 1.5 mg With Hydrochlorothiazide 25 mg, in Combination With an ACE-inhibitor, in Old Patients With Mild to Moderate Renal Insufficiency and Hypertension

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: West China Hospital · Academic / Other
• Sex: All
• Age: 65 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effects of indapamide SR 1.5 mg on renal function, endothelial function, blood pressure variability by comparison with hydrochlorothiazide 25 mg, in patients with Mild to Moderate Renal Insufficiency and Hypertension.

Conditions

• Hypertension
• Renal Insufficiency

Interventions

Type	Name	Description
DRUG	Indapamide	Indapamide SR 1.5mg qd
DRUG	Hydrochlorothiazide	Hydrochlorothiazide 25mg qd

Timeline

• Start date: 2010-09-01
• Primary completion: 2012-03-01
• Completion: 2013-12-01
• First posted: 2010-07-29
• Last updated: 2014-06-24

Locations

1 site across 1 country: China