NCT01171547

Daptomycin Pharmacokinetics in Continuous Veno-venous Hemodiafiltration

Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Find Study

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose is to investigate daptomycin pharmacokinetics in critically ill patients with suspected or verified bacteremia with Gram-positive cocci undergoing combined continuous hemodiafiltration at a filtration rate of 35ml/kg/h and to establish a dose recommendation for continuous hemodiafiltration at a filtrate rate of 35ml/kg/h.

Conditions

• Bacteremia

Interventions

Type	Name	Description
DRUG	Daptomycin	once daily over 5 days

Timeline

• Start date: 2010-02-01
• Primary completion: 2010-02-01
• First posted: 2010-07-28
• Last updated: 2010-07-28

Locations

1 site across 1 country: Switzerland