NCT01170494

Effect of Vitamin D Oral Supplements on 25 OH Vitamin D Levels

Effect of Vitamin D Oral Supplements on 25 OH Vitamin D Levels: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 279 (actual)
• Sponsor: King Faisal Specialist Hospital & Research Center · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Vitamin D deficiency is common world wide. 25 OH vitamin D level is the best indicator of vitamin D status. Vitamin D supplements are available as vitamin D2 or D3, in small daily or large weekly/monthly doses. Controversy continues on the relative potency of vitamin D2 compared to D3 and of daily compared to weekly or monthly doses, in increasing/maintaining total 25 OH vitamin D level. The investigators plan to conduct a controlled trial to compare the effect of various vitamin D supplements on 25 OH vitamin D levels in healthy adults with starting 25 OH vitamin D level between 20 to 50 nmol/L.

Conditions

• Vitamin D Deficiency

Interventions

Type	Name	Description
DRUG	ergocalciferol 2000 IU orally, daily	ergocalciferol 2000 IU orally, daily
DRUG	ergocalciferol 25000 IU oraly every 2 weeks	ergocalciferol 25000 IU oraly every 2 weeks
DRUG	ergocalciferol 50000 IU orally every 4 weeks	ergocalciferol 50000 IU orally every 4 weeks
DRUG	ergocal1000 IU & cholecal 1000 IU orally daily	ergocalciferol 1000 IU and cholecalciferol 1000 IU orally every day
DRUG	cholecalciferol 2000 IU orally daily	cholecalciferol 2000 IU orally everyday
DRUG	Cholecalciferol 25000 IU orally every 2 weeks	Cholecalciferol 25000 IU orally every 2 weeks
DRUG	Cholecalciferol 50000 orally every 4 weeks	Cholecalciferol 50000 orally every 4 weeks
DRUG	placebo orally everyday	placebo orally everyday

Timeline

• Start date: 2013-02-01
• Primary completion: 2016-04-01
• Completion: 2016-04-01
• First posted: 2010-07-27
• Last updated: 2016-08-31

Locations

1 site across 1 country: Saudi Arabia