NCT01167387

Preoperative Carbohydrate Loading in Elective Surgery

PREOPERATIVE ORAL CARBOHYDRATE LOADING: EFFECTS ON THE GLUCOSE METABOLISM AND POSTOPERATIVE INFECTIONS

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 880 (actual)
• Sponsor: University of Milano Bicocca · Academic / Other
• Sex: All
• Age: 19 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Postoperative infectious morbidity remain the most frequent, threatening and costly event after major surgery. Maintenance of postoperative euglycemia might be a key factor to prevent such complications and given the preliminary data on the positive effect of carbohydrate load on glucose metabolism it might also be valuable in improving outcome. If this treatment will be proved effective on relevant outcome measure such as rate of infections, it might be used routinely and extensively because preoperative carbohydrates administration is cheap, simple and applicable by everyone in any surgical ward. The aim of the trial is to evaluate if the normalization of blood glucose by means of preoperative oral administration of maltodextrine, in patients candidate to elective major surgery, may be effective in improve surgical morbidity.

Conditions

• Surgery

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	PREOP	a carbohydrate beverage (total carbohydrates equal to 12.6g/100 mL: 2.1 g monosaccharide, 10.0 g maltodextrine; 240 mOsm/L) in dose of 800 mL
OTHER	water	The control group will receive plain water with the same volume and timing of treatment.

Timeline

• Start date: 2011-01-01
• Primary completion: 2015-12-01
• Completion: 2016-03-01
• First posted: 2010-07-22
• Last updated: 2016-08-08

Locations

1 site across 1 country: Italy