NCT01166165

Effect of Vitamin D Replacement During Winter Months in Patients With Hypertension

Effect of Cholecalciferol on 24-hr ABPM and Vasoactive Hormones in Patients With Hypertension.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 136 (actual)
• Sponsor: Regional Hospital Holstebro · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

High blood pressure is related to increased risk of cardiovascular disease and death, and accounts for approximately 8 mill deaths worldwide each year. Blood pressure exhibits a seasonal variation with a tendency to increase during winter months. Vitamin D deficiency is more common during months where UVB radiation from the sun is absent, and vitamin D has been associated with high blood pressure. This study will evaluate the effect of vitamin D replacement during winter months on blood pressure and vasoactive hormones in patients with high blood pressure.

Conditions

• Hypertension
• Vitamin D Deficiency

Interventions

Type	Name	Description
DRUG	Cholecalciferol	3 tablets of 1000 IU daily for 20 weeks
DRUG	Placebo	3 placebo tablets daily for 20 weeks

Timeline

• Start date: 2010-07-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2010-07-20
• Last updated: 2012-06-19

Locations

1 site across 1 country: Denmark