NCT01165619

Detailed Clinical, Biochemical and Genetic Characterization in Gonadotropin-releasing Hormone (GnRH) Deficiency Disorders

Detailed Clinical, Biochemical and Genetic Characterization in GnRH Deficiency Disorders

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

In this study, we will measure levels of reproductive hormones and metabolic markers in subjects with isolated GnRH deficiency disorders and compare them to healthy control populations. Our goals are (1) to chart the range of hormonal and metabolic biomarkers in healthy subjects and those with reproductive disorders and (2) to correlate reproductive and metabolic phenotypes with genetic changes within patients with reproductive disorders and healthy controls.

Conditions

• Idiopathic Hypogonadotropic Hypogonadism
• Hypothalamic Amenorrhea

Timeline

• Start date: 2010-06-01
• Primary completion: 2010-10-01
• Completion: 2010-10-01
• First posted: 2010-07-20
• Last updated: 2011-05-24

Locations

1 site across 1 country: United States