Trials / Completed
CompletedNCT01163552
Heated Chemotherapy for Cancers That Have Spread to the Chest Cavity
Surgical Cytoreduction Followed by Intraoperative Intrathoracic Hyperthermic Chemotherapy Perfusion for the Management of Disseminated Pleural Malignancies
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 5 (actual)
- Sponsor
- St. Luke's-Roosevelt Hospital Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Cancers that have spread to the inner lining of the chest are classified as Stage IV and bear a poor prognosis. Surgery is rarely an option, with palliative chemotherapy and/or radiation therapy the only treatment options. This study intends to evaluate whether surgical removal of all visible tumor on the chest wall followed by bathing the chest cavity in heated chemotherapy solution will improve outcomes for these advanced cancers.
Conditions
- Pleural Metastases
- Breast Cancer
- Colon Cancer
- Ovarian Cancer
- Uterine Cancer
- Renal Cell Cancer
- Thymic Cancer
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Surgical debulking and Intrathoracic Hyperthermic Chemotherapy | Surgical debulking of intrathoracic metastases will be performed, followed by perfusion of the chest with heated Cisplatin for 60 minutes. |
Timeline
- Start date
- 2010-06-01
- Primary completion
- 2014-05-01
- Completion
- 2014-05-01
- First posted
- 2010-07-15
- Last updated
- 2014-06-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01163552. Inclusion in this directory is not an endorsement.