NCT01162902

Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Treatments for stable angina includes drug therapy such as calcium-channel blocker, beta blocker, and ACEI/ARB. To obtain good prognosis in patients with coronary artery disease,preventing or correcting the progression of atherosclerosis and dyslipidemia is more important than relieving angina symptom. Dysfunction of microvessel is one of the most important factor in patients with coronary artery disease. Recently, we developed the new non-invasive method of evaluating the microvessel in fundus. With this methods, we will compare the effect of each drug (beta blocker, CCB, ARB).

Conditions

• Stable Angina

Interventions

Type	Name	Description
DRUG	Diltiazem treated group	Diltiazem 180mg for 9 months
DRUG	Bisoprolol treated group	Bisoprolol 5mg for 9 months
DRUG	Candesartan treated group	Candesartan 32mg for 9 months

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-01-01
• Completion: 2015-12-01
• First posted: 2010-07-15
• Last updated: 2013-12-17

Locations

1 site across 1 country: South Korea