NCT01156129

Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection Surgery

Interventions to Decrease the Impact of Post-Operative Ileus After Liver Transplant or Resection Surgery

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 111 (actual)
• Sponsor: University of Nebraska · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized controlled trial to assess ways to address post-operative ileus (POI) in adult patients on the liver transplant service undergoing either liver transplant or resection surgery. Patient who speak and understand English will be randomized into one of three groups including a.)control group receiving standard therapy for post-operative ileus, b.)group receiving standard therapy and acupressure bracelets, and c.)group receiving standard therapy and sugar free gum four times daily.

Detailed description

Any patient undergoing liver transplant or resection surgery will be asked to participate in the study and assigned to a control or investigational group. Pertinent information will be collected from the medical record including gender, age in years, diagnosis, type of surgery, length of stay, medications used for pain or nausea, and first bowel movement. The subjects will also be asked to keep a journal of their bowel habits, signs and symptoms of gastrointestinal distress/post-operative ileus, use of medications, first bowel movement, satisfaction with bowel management and any additional comments. Aims of the study are to determine the effectiveness of the three arms of this trial for the resolution of POI as noted by first post-operative bowel movement; to determine if there is a difference in the length of stay based on the interventions; and to determine if there is a difference in patient satisfaction based on the intervention.

Conditions

• Ileus

Interventions

Type	Name	Description
DRUG	stool softener	ducosate sodium, Milk of Magnesia, dulcolax
DEVICE	Arm B: Acupressure bracelet	Bioband
DIETARY_SUPPLEMENT	sugar free gum	Orbit

Timeline

• Start date: 2010-09-01
• Primary completion: 2012-07-01
• Completion: 2012-12-01
• First posted: 2010-07-02
• Last updated: 2023-09-07

Locations

1 site across 1 country: United States