NCT01155440

Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine

Restoration of Bowel Function After Laparoscopic Colorectal Surgery: Effect of Intravenous Lidocaine

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients receiving perioperative intravenous lidocaine, post operative restoration of bowel movement will be faster and decrease pain intensity, opioid consumption and side effects, length of hospital stay; probably as a result of a significant opioid sparing and attenuated inflammatory response.

Detailed description

The aim of this study is to assess whether perioperative intravenous lidocaine has an impact on the early postoperative physical activity recovery of patients scheduled for laparoscopic colorectal resection. The study focuses on patients with colorectal disease, which receive the laparoscopic (assisted) surgical approach. It is hypothesized that in those patients receiving perioperative and post-operative intravenous lidocaine, bowel function recovery will be faster, probably as a result of a significant opioid sparing, less pain and attenuated inflammatory response.

Conditions

• Colon Cancer
• Inflammatory Bowel Diseases
• Diverticulitis

Interventions

Type	Name	Description
DRUG	Lidocaine	1% Lidocaine 1mg/kg/hr IV drip x 48hr
PROCEDURE	Thoracic epidural block	0.1% Epidural bupivacaine + Morphine 0.02 mg/ml drip via epidural x48 hr

Timeline

• Start date: 2009-06-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2010-07-01
• Last updated: 2011-11-28

Locations

1 site across 1 country: Canada