NCT01153243

Vitamin D and Inflammatory Markers of Cardiovascular Disease in African Americans With Type 2 Diabetes

Does Administration of Vitamin D in African Americans With Hypovitaminosis D and Type 2 DM Improve Inflammatory Markers of Cardiovascular Disease?

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 117 (actual)
• Sponsor: Cook County Health · Other Government
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Recent clinical trials in non diabetics showed that vitamin D supplementation markedly reduced serum levels of C-reactive protein (CRP), interleukin-6, and tissue matrix metallo-proteinases. Our study objective is to evaluate if administration of vitamin D in African Americans with hypovitaminosis D and DM Type 2 decreases serum levels of inflammatory/thrombotic markers such as CRP: Highly Sensitive C Reactive Protein.

Detailed description

Other questions in our study: In diabetic African American patients, 1. Prevalence of vitamin D deficiency? 2. Correlation/relationship between vitamin D levels, Calcium level, parathyroid hormone (PTH) and Inflammatory markers Setting: All visits will take place at the Fantus Diabetes Clinic.

Conditions

• Vitamin D Deficiency
• Diabetes

Interventions

Type	Name	Description
DRUG	Ergocalciferol	Active Comparator: Ergocalciferol The investigators will give intervention group 12 weeks of Vitamin D (ergocalciferol 50,000 units every week)
DRUG	Placebo pill	The investigators will give control group 12 weeks of 1 placebo pill every week.

Timeline

• Start date: 2007-04-01
• Primary completion: 2010-06-01
• Completion: 2011-06-01
• First posted: 2010-06-30
• Last updated: 2011-04-07