NCT01153035

Excision Followed by Radiofrequency Ablation for Breast Cancer

ABLATE Registry: Radiofrequency Ablation After Breast Lumpectomy (eRFA) Added To Extend Intraoperative Margins in the Treatment of Breast Cancer

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: Female
• Age: 50 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study will be to evaluate, in a multi-center setting, the ability of radiofrequency ablation (RFA) of breast cancer lumpectomy sites to extend the "final" negative margin and consequently decrease the rates of re-operation. During the initial breast conservation procedure (lumpectomy), immediately following routine surgical resection of the tumor, radiofrequency energy (RFA) is applied to the wall (bed) of the fresh lumpectomy cavity, thus extending tumor free margin radially beyond the volume of the resected specimen.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DEVICE	Radiofrequency Ablation	Breast conservation surgery followed by Radiofrequency Ablation of the cavity

Timeline

• Start date: 2010-06-01
• Primary completion: 2027-06-01
• Completion: 2027-06-01
• First posted: 2010-06-29
• Last updated: 2025-11-10

Locations

6 sites across 1 country: United States