NCT01148277

Propofol and Remifentanyl Versus Midazolam and Fentanyl for Diagnostic Colonoscopy in Patients With Compensated Cirrhosis Child A-B

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Ziv Hospital · Other Government
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective, randomized-controlled trial (RCT) comparing the use of Propofol and Remifentanyl and traditional sedation (Midazolam and Fentanyl) for diagnostic colonoscopies in patients with compensated cirrhosis child A-B. The working hypothesis is that the use of propofol will be translated in a shorter recovery and discharge times with a higher patient satisfaction and a decrease in general complications (Hepatic Encephalopathy) in the context of patients with advanced liver disease.

Conditions

• Liver Disease

Interventions

Type	Name	Description
DRUG	Propofol and Remifentnyl	Intervention group (Propofol and remifentanyl): It will be administered under direct gastroenterologists' and hepatologist
DRUG	midazolam and fentanyl	Intervention group (Propofol and fentanyl ): It will be administered under direct gastroenterologists'and hepatologist
DRUG	midazolam anf fentanyl	group (Midazolam with Fentanyl): Both drugs will be administered by the gastroenterologists and/ or hepatologist and/ or anesthiologist

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-02-01
• Completion: 2012-02-01
• First posted: 2010-06-22
• Last updated: 2011-04-06

Locations

1 site across 1 country: Israel