Clinical Trials Directory

Trials / Terminated

TerminatedNCT01148264

Comparison of Olanzapine and Metoclopramide For Treatment Of bReakThrough Emesis

Efficacy of Olanzapine in Break-through Emesis After Prophylaxis With Dexamethasone, 5-HT3 Receptor Antagonists and Aprepitant Compared to Metoclopramide

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
23 (actual)
Sponsor
Karin Jordan · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This trial is designed to evaluate olanzapine compared to the metoclopramide in the treatment of break through emesis after prophylaxis with dexamethasone, 5-HT 3 receptor antagonists and aprepitant in patients receiving chemotherapy. Efficacy will be assessed using a modified MASCC questionaire with a visual analog scale.

Conditions

Interventions

TypeNameDescription
DRUGolanzapine1x10mg per day for three days
DRUGmetoclopramide3x10mg per day for three days

Timeline

Start date
2010-07-01
Primary completion
2013-10-01
Completion
2014-10-01
First posted
2010-06-22
Last updated
2016-05-11

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT01148264. Inclusion in this directory is not an endorsement.