NCT01147510

Asthma Control in Elderly Patients With Montelukast

A Randomized Controlled Study of Montelukast Plus Low Dose Inhaled Budesonide Versus Medium Dose Inhaled Budesonide on Asthma Control in Elderly Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: Ajou University School of Medicine · Academic / Other
• Sex: All
• Age: 60 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

To compare the efficacy of combination therapy of montelukast plus low dose inhaled budesonide and single therapy of medium dose inhaled budesonide on asthma control such as inflammatory markers and clinical indicators and to compare treatment response according to leukotriene related genotypes in elderly patients with asthma

Conditions

• Persistent Asthma
• Elderly

Interventions

Type	Name	Description
DRUG	Combination of low ICS and montelukast	Two puffs of Pulmicort ® turbuhaler 200µg/puff between 7 a.m. and 10 a.m and take orally a tablet of Singulair® 10mg one time per day.
DRUG	Monotherapy of medium dose ICS	Two puffs of Pulmicort ® turbuhaler 200µg/puff between 7 a.m. and 10 a.m. and between 7 p.m. and 10 p.m. two times per day

Timeline

• Start date: 2010-07-01
• Primary completion: 2012-09-01
• Completion: 2012-09-01
• First posted: 2010-06-22
• Last updated: 2013-11-13

Locations

1 site across 1 country: South Korea