NCT01146405

Memory During Anesthesia: the Role of Stress Hormones

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 110 (estimated)
• Sponsor: Catholic University of the Sacred Heart · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

1. To investigate whether the auditory stimulation causes changes in hormones levels (cortisol+prolactin) during general anesthesia. 2. To determine if there is a correlation between hormones levels (cortisol+prolactin) and dreams recall. 3. To investigate whether, in patients receiving auditory stimulation, there is a correlation between hormones levels (cortisol+prolactin), serum remifentanil concentration and detection of implicit memory. 4. To investigate the presence of primary auditory cortex activation (temporal lobe) in patients with implicit memory and in those with dreams recall using the EEG-ERP 128 channels GES300 EGI system.

Detailed description

Patients from group A, during maintenance of anesthesia, at the time of trocar insertion, will listen (via MP3) a piece of one of two stories, "Puss in Boots" and "Pinocchio", each followed by four keywords. In group B, patients will be isolated from the sounds of the operating room using specific headphones.

Conditions

• Surgical Procedure, Unspecified

Timeline

• Start date: 2010-06-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2010-06-17
• Last updated: 2011-02-09

Locations

1 site across 1 country: Italy