NCT01145534

Evaluation of Cissus Verticillata L. Infusion in Controlling Type 2 Diabetes

Phase 1 Study for Testing Efficacy of Cissus Verticillata L Infusion in Controlling Glucose Concentration

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Federal University of Paraíba · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to investigate whether the infusion of a medicinal plant (Cissus verticillata L.) would be effective in reducing glucose levels in blood and saliva of type 2 Diabetes patients.

Detailed description

Type 2 diabetes mellitus is regarded as one of the most prevalent disease of the adult population. In many developing countries, this condition is regarded as major public health problem. Type 2 diabetes is a metabolic disorder characterized by high blood glucose related with a condition of insulin resistance and relative insulin deficiency. As Diabetes progresses, medications are necessary to control glucose levels. The aim of this study was to investigate whether the infusion of a medicinal plant (Cissus verticillata L.) would be as effective as a regular drug (glibenclamide) in reducing glucose levels in blood and saliva of type 2 Diabetes patients. Several medicinal plants have been used as potential medication for controlling glucose levels in Diabetes patients. Few studies have explored this effect related to Cissus verticillata L.infusion, though it has been indicated by folk medicine of some Latin American countries.

Conditions

• Diabetes

Interventions

Type	Name	Description
DRUG	glibenclamide	5 mg as pills, taken daily during the morning for 60 days
OTHER	medicinal plant infusion	INfusion fo Cissus verticillata L., 1 g in 150 mL water, ingested daily for 60 days.

Timeline

• Start date: 2009-01-01
• Primary completion: 2009-08-01
• Completion: 2009-10-01
• First posted: 2010-06-16
• Last updated: 2011-11-09

Locations

1 site across 1 country: Brazil