NCT01143974

Trial of Pemetrexed in Combined With Cisplatin for the Treatment of Advanced Breast Cancer

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Chinese Academy of Medical Sciences · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

For patients resistant to enthrycycline and taxanes, there is no standard regimen. Pemetrexed alone had certain efficacy in treatment of advance breast cancer. Platin was also a effective drug for advanced breast cancer. The combination of these two drug may have a synergy with each other in treatment of advanced breast cancer.

Detailed description

combination of pemetrexed and cisplatin to treat advanced breast cancer. Previous regimen no more than 3 which including enthrycycline and taxanes(paclitaxel and/or docetaxel)

Conditions

• Locally Advanced Malignant Neoplasm

Interventions

Type	Name	Description
DRUG	pemetrexed plus cisplatin	pemetrexed 500mg/m2 plus cisplatin 80mg/m2 on day1 of each 21 day cycle, until progression

Timeline

• Start date: 2010-06-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2010-06-15
• Last updated: 2013-03-14

Locations

1 site across 1 country: China