NCT01142258

Trazodone for Sleep Disorders in Alzheimer's Disease

Trazodone for the Treatment of Sleep Disorders in Alzheimer's Disease: a Randomised, Double-blind, Placebo-controlled Study

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Brasilia University Hospital · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether trazodone is effective in the treatment of sleep disorders in Alzheimer's disease (AD).

Detailed description

Sleep disorders (SD) affects 35 to 50 percent of patients with AD. These disorders often make caring for patients at home very difficult. Trazodone is commonly prescribed drugs for SD in AD patients. There are no controlled studies in this sample of patients for this purpose.

Conditions

• Sleep
• Sleep Disorders
• Insomnia
• Alzheimer's Disease

Interventions

Type	Name	Description
DRUG	Trazodone	Trazodone tablets, 50 mg, 10pm (before bedtime) for 14 days.
DRUG	Placebo	Inactive or inert pill which will be used as a comparator

Timeline

• Start date: 2010-03-01
• Primary completion: 2012-04-01
• Completion: 2012-08-01
• First posted: 2010-06-11
• Last updated: 2012-10-15

Locations

1 site across 1 country: Brazil